Neurotoxicity of methylglyoxal to differentiation of hippocampal neural stem cells and protective effect of Naokang Ⅱ in adult rats
甲基乙二醛对成年大鼠海马干细胞分化的神经毒性及脑康Ⅱ号保护作用的研究
Objective To investigate the effect of methylglyoxal(MGO) on hippocampal neuronal cells and to discuss the possible mechanism.
目的:探讨甲基乙二醛对大鼠海马神经元的损伤作用及其可能机制。
Recent studies have demonstrated that endogenous accumulation of methylglyoxal in the diabetic patients may result in numerous pathogenic processes in vivo,including re- nal dysfunction,cardiovascular diseases,cataract or aging.
甲基乙二醛(MG)是人体内糖代谢产生的一种毒性副产物,糖屎病患者体内MG显著增加。
